IL-1 beta Antibody
- 貨號 Cat. No.
- 5129-100
- 規格 Size
- 100 µg
Description
pstrongAntibody Target :/strongIL-1b/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bE. coli expressed murine IL-1beta;/p
pbAccession#: /bCAA28637/p
pbGene ID: /b52667/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity purified rabbit anti-murine IL-1beta; polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5%BSA and 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bms/p
pbApplication: /bWB/NL/p
pbApplication amp; Usage: /bWestern blot analysis (0.5-4 micro;g/ml). Recombinant murine IL-1beta; (Cat.# 4129-10) can be used as a positive control. Per researcherrsquo;s feedback, the antibody can also be used in neutralization studies. However, the optimal conditions should be determined individually./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bIL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Recombinant murine IL-1beta is a 17.5 kDa protein containing 153 amino acid residues./p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bE. coli expressed murine IL-1beta;/p
pbAccession#: /bCAA28637/p
pbGene ID: /b52667/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity purified rabbit anti-murine IL-1beta; polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5%BSA and 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bms/p
pbApplication: /bWB/NL/p
pbApplication amp; Usage: /bWestern blot analysis (0.5-4 micro;g/ml). Recombinant murine IL-1beta; (Cat.# 4129-10) can be used as a positive control. Per researcherrsquo;s feedback, the antibody can also be used in neutralization studies. However, the optimal conditions should be determined individually./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bIL-1beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Recombinant murine IL-1beta is a 17.5 kDa protein containing 153 amino acid residues./p