IKKa/IKK-1 Antibody
- 貨號 Cat. No.
- 3185-100
- 規格 Size
- 100 µg
Description
pstrongAntibody Target :/strongIKKa/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bE. coli expressed recombinant human IKKa/p
pbAccession#: /bNP_001269/p
pbGene ID: /b1147/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) Protein A purified rabbit anti-IKKalpha; polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/p
pbApplication: /bWB/IP/p
pbApplication amp; Usage: /bWestern blot (at 0.5-1 micro;g/ml) and immunoprecipitation (4-8 micro;g/ml). However, the optimal conditions should be determined individually./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bIKKalpha; (IkB kinase-alpha; or IKK-1) is part of a large protein complex responsible for the inducible phosphorylation of IkB proteins. Human IKK-alpha; is an 85 kDa peptide that has been shown to activate NFkB by phosphorylation of IkB proteins. IKKalpha; interacts with its upstream kinase, NIK, and its downstream substrate, the IkB proteins. Mutations of IKKalpha; in its kinase domain lead to a dominant-negative phenotype that suppresses TNF-alpha; and IL-1beta; induced NFkB activation./p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bE. coli expressed recombinant human IKKa/p
pbAccession#: /bNP_001269/p
pbGene ID: /b1147/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) Protein A purified rabbit anti-IKKalpha; polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/p
pbApplication: /bWB/IP/p
pbApplication amp; Usage: /bWestern blot (at 0.5-1 micro;g/ml) and immunoprecipitation (4-8 micro;g/ml). However, the optimal conditions should be determined individually./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bIKKalpha; (IkB kinase-alpha; or IKK-1) is part of a large protein complex responsible for the inducible phosphorylation of IkB proteins. Human IKK-alpha; is an 85 kDa peptide that has been shown to activate NFkB by phosphorylation of IkB proteins. IKKalpha; interacts with its upstream kinase, NIK, and its downstream substrate, the IkB proteins. Mutations of IKKalpha; in its kinase domain lead to a dominant-negative phenotype that suppresses TNF-alpha; and IL-1beta; induced NFkB activation./p