IkBa Antibody

貨號 Cat. No.
3252-100
規格 Size
100 µg

Description

pstrongAntibody Target :/strongIkBa/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bE. coli expressed mouse IkBa/p
pbAccession#: /bQ9Z1E3/p
pbGene ID: /b61226507/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.2 mg/ml/p
pbFormulation: /b100 micro;g (0.2 mg/ml) affinity-purified rabbit anti-IkB-alpha polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, and 0.02% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bms/p
pbApplication: /bWB/p
pbApplication amp; Usage: /bWestern blot (0.5-4 micro;g/ml). However, the optimal conditions should be determined individually. Cross-reactivity to I?B-alpha of other species has not been determined./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bIkB-alpha protein is a NF-kB inhibitory protein. It binds NF-kB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus and functioning as a transcription factor. Upon receiving a variety of signals, IkB-alpha undergoes phosphorylation at serine residues by an ubiquitin-dependent protein kinases and finally degraded by the proteasome. Free NF-kB then binds DNA and affects gene expression./p

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