IGF-BP5 Antibody
- 貨號 Cat. No.
- 5723-100
- 規格 Size
- 100 µg
Description
Antibody Target :IGFBP-5
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Antibody Form: Affinity Purified Antibody
Immunogen Sequence: E. coli expressed human IGF-BP5
Accession#: NP_000590
Gene ID: 3488
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation:
Purification: Affinity purified
Species Reactivity: hu
Application: WB
Application & Usage:
Storage Temp.: -20 °C
Shipping : gel pack
Shelf Life: 12 months
Handling: The antibody solution should be gently mixed before use.
Brief Background Descriptions: Human IGF-BP5 is a cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Studies show that IGF-BP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGF-BP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole body growth inhibition, and retarded muscle development.