Kits
ID-Vit® Niacin direct MTP assay
Kits
Description
Niacin (nicotinic acid and nicotinamide) is used by the body to form coenzymes such
as nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide
phospate (NADP+). As many as 200 enzymes require the two coenzymes, NAD+
and NADP+, mainly to accept or donate electrons for redox reactions. NAD+ functions
most often in reactions involving the degradation (catabolism) of carbohydrates,
fats, proteins, and alcohol to produce energy. NADP+ functions more often in biosynthetic
(anabolic) reactions, such as in the synthesis of fatty acids and cholesterol.
Since almost every metabolic pathway uses either NAD+ or NADP+, it is not surprising
to find signs and symptoms of niacin deficiency in severe metabolic disorders. The
worst of these is pellagra which is characterized by the four Ds, representing dermatitis,
diarrhoea, dementia and death.
as nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide
phospate (NADP+). As many as 200 enzymes require the two coenzymes, NAD+
and NADP+, mainly to accept or donate electrons for redox reactions. NAD+ functions
most often in reactions involving the degradation (catabolism) of carbohydrates,
fats, proteins, and alcohol to produce energy. NADP+ functions more often in biosynthetic
(anabolic) reactions, such as in the synthesis of fatty acids and cholesterol.
Since almost every metabolic pathway uses either NAD+ or NADP+, it is not surprising
to find signs and symptoms of niacin deficiency in severe metabolic disorders. The
worst of these is pellagra which is characterized by the four Ds, representing dermatitis,
diarrhoea, dementia and death.