IAA (Insulin Autoantibody) ELISA

pIAA (Insulin Autoantibody) br /
ELISAbr /
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pimg alt=For Research Use Only src=http://www.alpco.com/img/ruo.gif align=absMiddle / For Research Use Only/p
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div class=prod_specbFormat:/b/div
div class=prod_spec_infoELISA / EIA/div
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div class=prod_spec_info25 micro;l/div
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div class=prod_spec_info96 Wells/div
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pbSummary:/b/p
IAA (Insulin Autoantibody) EIA - Qualitative ELISA test for the detection of circulating autoantibodies against human insulin. Insulin-dependent diabetes mellitus (IDDM) or Type I Diabetes is an autoimmune disease in which insulin deficiency is a consequence of immunological destruction of the pancreatic beta cells. In individuals who are genetically predisposed to IDDM, the immunological attack on the beta cells occurs during an asymptomatic period (1) which is referred to as the quot;Prediabetic Phasequot;. This prediabetic phase usually begins several years before the clinical onset of IDDM. During this phase, autoantibodies directed against pancreatic islet cell antigens (ICA) and/or insulin (IAA) are detected in the blood of many prediabetic subjects.(1) Eisenbarth, GS, J. Connelly, and J.S. Soeldner (1987). The natural history of type I diabetes. Diabet./Metab. Rev./ 3:873-891./div
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