Kits
Hydroxy Pyridinium Crosslinks (PYD/DPD), HPLC
- 貨號 Cat. No.
- KC3201
- 規格 Size
- 100 Tests
- 品牌 Brand
- IDS
Description
| Article number: | KC3201 |
| Method: | HPLC |
| Tests: | 100 Tests |
| Matrix: | Urine |
| Volume: | 1 ml |
| Detection Elution: | Fluorescence |
| Standards: | isocratic |
| The hydroxypyridinium compounds pyridinoline (PYD) and deoxypyridinoline (DPD) are specific constituents of mature skeletal collagens. They are released into the circulation and excreted in the urine. Their measurement in urine is a sensitive index of the extent of ongoing bone resorption. The quantification of collagen Crosslinks in urine is achieved by chromatographic techniques. Clinical applications of hydroxypyridinium markers include numerous metabolic bone disorders such as osteoporosis, primary hyperparathyroidism, Paget´s disease of bone, and metastatic bone disease. Urinary pyridinium Crosslinks of collagen also show great promise as markers of therapeutic efficacy in bone disorders associated with accelerated bone resorption |