Hyaluronidase-1 Antibody

Hyaluronidase-1 plays a role in promoting tumor progression. Hyaluronidase-1 blocks TGFB1-enhanced cell growth. Defects in hyaluronidase-1 are the cause of mucopolysaccharidosis type 9, also called hyaluronidase deficiency. MPS9 is a lysosomal storage disease characterized by high hyaluronan (HA) concentration in the serum. The clinical features are periarticular soft tissue masses, mild short stature and acetabular erosions, and absence of neurological or visceral involvement.