Human VEGFR2 / Flk-1 / CD309 / KDR Protein (His Tag)

Species : Human

Synonyms : CD309,Flk-1,FLK1,VEGFR,VEGFR2

Host : HEK293 Cells

Purity :> 97 % as determined by SDS-PAGE

Activity : 1. Using the Octet RED System, the affinity constant (Kd) of human VEGFR2-his bound to biotinylated human VEGF165 was 5.9 nM.
2. Using the Octet RED System, the affinity constant (Kd) of VEGFR2 / KDR Protein, Human, Recombinant (His Tag) (Cat. 10012-H08H) bound to Anti-VEGFR2 Antibody (Cat. 10012-MM03) was 1.9 £gM.
3. Measured by its ability to inhibit the VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 10-50£gg/mL in the presence of 10 ng/mL recombinant human VEGF165.