Human VEGFR1 / FLT-1 Protein (Fc Tag)

Species : Human

Synonyms : FLT,FLT-1,VEGFR-1,VEGFR1

Host : HEK293 Cells

Purity :> 95 % as determined by SDS-PAGE.

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized human VEGFR1-Fc(Cat:10136-H02H) at 10£gg/mL (100£gL/well) can bind biotinylated human VEGF165 (Cat:11066-HNAH), the EC50 of biotinylated human VEGF165 is 10-40 ng/mL.
2. Measured by its ability to inhibit VEGF-dependent proliferation of human umbilical vein endothelial cells (HUVEC). The ED50?for this effect is typically 20-100 ng/mL in the presence of 10 ng/mL rhVEGF165.