Human TrkC ELISA Kit (2 Plate)

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Ntrk3; NT-3 growth factor receptor; GP145-TrkC; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Please download the detailed product insert for complete instructions for the successful use of this ELISA; Use only as directed.

 

Background_Info : TrkC is a member of the neurotrophic tyrosine receptor kinase family. TrkC is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkC is the receptor for neurotrophin-3 (NT-3).Signalling through TrkC leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. SUBUNIT: Exists in a dynamic equilibrium between monomeric (low affinity) and dimeric (high affinity) structures. SUBCELLULAR LOCATION: Membrane; single-pass type I membrane protein. ALTERNATIVE PRODUCTS: 4 named isoforms produced by alternative splicing. Additional isoforms seem to exist. Mutations in TrkC have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : https://www.biosensis.com/pdf_datasheet.php?products_id=1756

 

Description (Long Description) : 

The Biosensis Creatinine (Urinary) Colorimetric Assay can be used to measure creatinine levels in urine. The assay relies on the Jaffe’ reaction, wherein a yellow/orange color forms when the metabolite is treated with alkaline picrate (2). The color derived from creatinine is then destroyed at acidic pH. The difference in color intensity measured at 500 nm before and after acidification is proportional to the creatinine concentration (1,3-4). The sample creatinine concentration is determined using a creatinine standard curve. The Creatinine (Urinary) Colorimetric Assay is not recommended for plasma or serum samples. Assay precision has been determined to be 2.7% (intra-assay, n = 84) and 3.0% (inter-assay, n=5). This assay kit has not been tested for other applications. It has been configured for research use only and is not to be used for diagnostic or clinical procedures.

 

Expiry_Date : 

Refer to expiration date on the outside of the box.

 

Format (Form) : 

Ready to use Assay, complete with Detection reagents and complete instructions.

 

Immunogen (Antigen) :Recombinant protein fragment from human TrkC; Immunogen sequence: C32-A428

 

Kit_Components : The ELISA kit box contains 2 x 96-well pre-coated strip plates, human TrkC protein standards, human TrkC biotinylated antibody, Avidin-Biotin-Peroxidase Complex, sample, antibody and avidin-biotin peroxidase diluents, substrate reagent, stop solution, wash buffer, plate sealers and detailed protocols.

 

MSDS (File name) :https://www.biosensis.com/pdf_MSDS.php?products_id=1756