Human TrkB-Fc Chimera expressed in mammalian cells
Proteins and Peptides
- 貨號 Cat. No.
- PE-1235-20
- 規格 Size
- 20 µg
- 品牌 Brand
- Biosensis
- Application 應用
- CC, Cell Culture
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Tropomyosin-related kinase receptor; BDNF/NT-3 growth factors receptor; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; GP145-TrkB/GP95-TrkB; Trk-B; Ntrk2; Trkb; TrkB-Fc Chimera
Antibody_Isotype
(Antibody only) :
Application_Details :
The TrkB-Fc chimera bound to protein A sepharose beads is able to pull down its ligand BDNF. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) :
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=913
Description (Long Description) :
Tyrosine Kinase Receptor B (TrkB) is a high affinity receptor for brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5. It also binds neurotrophin 3 (NT-3) with lower affinity. TrkB does not bind nerve growth factor (NGF). TrkB is involved in the development and/or maintenance of the nervous system and is widely expressed, predominantly in nervous tissue. TrkB is a heavily glycosylated type I transmembrane protein. The TrkB-Fc chimera contains 13 potential N-linked glycosylation sites.
Expiry_Date :
Format (Form) :
The chimera consists of 20-40% carbohydrate by weight.
Immunogen (Antigen) :
Kit_Components :
MSDS (File name) :
