Human Transferrin R / CD71 Protein, His Tag

Source : 

Human Transferrin R, His Tag (CD1-H5243) is expressed from human 293 cells (HEK293). It contains AA Cys 89 - Phe 760 (Accession # P02786-1).

 

Molecule : Transferrin R

 

Synonyms : CD71,TFRC,TFR,sTfR,TfR1,Trfr,T9,p90

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_003225.2

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 77.0 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 77.0 kDa. The protein migrates as 80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

 

References :

(1) Aisen P., 2004, Int. J. Biochem. Cell Biol. 36 (11): 2137–43.
(2) Moos T., 2002, Danish Medical Bulletin 49 (4): 279–301.