Human TRAIL R4 / TNFRSF10D Protein, His Tag

Source : 

Human TRAIL R4, His Tag (TR4-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ala 56 - His 211 (Accession # NP_003831).

 

Molecule : TRAIL R4

 

Synonyms : TNFRSF10D,CD264,TRAILR4,DCR2,TRUNDD

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_003831

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 18.7 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.7 kDa. The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) is also known as Decoy receptor 2 (DcR2), TNF-related apoptosis-inducing ligand receptor 4 (TRAIL receptor 4 or TRAIL-R4), CD264,which is the single-pass type I membrane protein. TNFRSF10D is receptor for the cytotoxic ligand TRAIL, which contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis.

 

References :

(1) Degli-Esposti M.A., et al., 1997, Immunity 7:813-820.
(2) Marsters S.A., et al, 1997, Curr. Biol. 7:1003-1006.
(3) Pan G., et al., 1998, FEBS Lett. 424:41-45.