Human TNFR2 / CD120b / TNFRSF1B Protein (ECD, His Tag)

Species : Human

Synonyms : CD120b,p75,p75TNFR,TBPII,TNF-R-II,TNF-R75,TNFBR,TNFR1B,TNFR2,TNFR80

Host : HEK293 Cells

Purity :> 97 % as determined by SDS-PAGE

Activity : 1. Measured by its ability to inhibit TNF-£ mediated cytotoxicity in L-929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.2-0.8 £gg/ml in the presence of 0.25 ng/mL recombinant human TNF-£.
2. Measured by its binding ability in a functional ELISA. Immobilized Human TNF-alpha (Cat:10602-HNAE) at 2 £gg/ml (100 £gl/well) can bind Human TNFR2/TNFRSF1B His(Cat:10417-H08H), the EC50?of Human TNFR2/TNFRSF1B His is 2.0-12.0 ng/mL.