Human TNFR1 / CD120a / TNFRSF1A Protein (His Tag)

Species : Human

Synonyms : CD120a,FPF,MS5,p55,p55-R,p60,TBP1,TNF-R,TNF-R-I,TNF-R55,TNFAR,TNFR1,TNFR1-d2,TNFR55,TNFR60

Host : HEK293 Cells

Purity :> 92 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA.
Immobilized human TNFRI-His at 10 £gg/mL (100 £gl/well) can bind biotinylated human TNF£. The EC50 of biotinylated human TNF£ is 5-12 £gg/mL.
2. Measured by its ability to inhibit TNF£-mediated cytotoxicity in L929 mouse fibrosarcoma cells in the presence of metabolic inhibitor actinomycin D. The ED50 for this effect is typically 0.2-1£gg/mL in the presence of 0.25 ng/mL recombinant human TNF£.