Human THSD1 Protein, His Tag

Source : 

Human THSD1, His Tag (TH1-H52H5) is expressed from human 293 cells (HEK293). It contains AA Glu 25 - Ile 361 (Accession # AAH63842).

 

Molecule : THSD1

 

Synonyms : THSD1,TMTSP

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : AAH63842

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 39.7 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.7 kDa. The protein migrates as 57-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Thrombospondin type-1 domain-containing protein 1 (THSD1) is also known as Transmembrane molecule with thrombospondin module (TMTSP), which is a single-pass type I membrane protein and contains a type 1 thrombospondin domain that is found in thrombospondin, a number of proteins involved in the complement pathway, as well as extracellular matrix proteins. In addition, THSD1 is widely expressed on endothelial cells, with highest expression in the lung. THSD1's ligand and function are unknown, but it is postulated that THSD1 may be involved in the regulation of vasculogenesis and/or angiogenesis through its interaction with its specific ligand.

 

References :

(1) Clark H.F., et al., 2003, Genome Res. 13:2265-2270.
(2) Bork P.,1993, FEBS Lett. 327 (2): 125–30.
(3) Clark HF., et al., 2003, Genome Res. 13 (10): 2265–70.