Human Serpin H1 Protein, His Tag

Source : 

Human Serpin H1, His Tag (SE1-H5224) is expressed from human 293 cells (HEK293). It contains AA Ala 19 - Leu 418 (Accession # P50454-1).

 

Molecule : Serpin H1

 

Synonyms : SERPINH1,Serpin H1,HSP47,CBP1,CBP2,SERPINH2,PIG14,AsTP3,Colligin,OI10,PPROM,RA-A47,gp46

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : NP_001226.2

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 45.5 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.5 kDa. The protein migrates as 47 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Serpin H1 is also known as SERPINH1, 47 kDa heat shock protein (HSP47), Collagen-binding protein (Colligin), Arsenic-transactivated protein 3 (AsTP3), which belongs to the serpin family. SERPINH1 binds specifically to collagen. SERPINH1 / HSP47 could be involved as a chaperone in the biosynthetic pathway of collagen.

 

References :

(1) Hattori T., et al., 2000, J. Bone Miner. Metab. 18:328-334.
(2) Christiansen H.E., et al., 2010, Am. J. Hum. Genet. 86:389-398.