Human SCARB2 / SR-B2 / LIMPII Protein, Fc Tag

Source : 

Human SCARB2, Fc Tag (SC2-H5250) is expressed from human 293 cells (HEK293). It contains AA Arg 27 - Thr 432 (Accession # AAH21892).

 

Molecule : SCARB2

 

Synonyms : SCARB2,CD36L2,LIMP2,LIMPII

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : AAH21892

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 72.6 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.6 kDa. The protein migrates as 90-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 100 mM Glycine, pH7.5

 

Description :

Scavenger receptor class B member 2 (SCARB2) is also known as Lysosome membrane protein 2 (LIMP2), 85 kDa lysosomal membrane sialoglycoprotein (LGP85), CD36 antigen-like 2 (CD36L2, LIMP2), which belongs to the CD36 family. SCARB2 acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.

 

References :

(1) Reczek D., et al., 2007, Cell 131:770-783.
(2) Schroeder B., et al., 2007, Traffic 8:1676-1686.
(3) Chen R., et al., 2009, J. Proteome Res. 8:651-661.