Human S100P / S100E Protein, Tag Free

Source : 

Human S100P, Tag Free (S1P-H5110) is expressed from E.coli cells. It contains AA Met 1 - Lys 95 (Accession # AAH06819).

 

Molecule : S100P

 

Synonyms : S100P,S100E,MIG9

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : AAH06819

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 10.4 kDa

 

Characteristics :

This protein carries no "tag". The protein has a calculated MW of 10.4 kDa. The protein migrates as 10.4 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 150 mM NaCl, pH8.0

 

Description :

S100 calcium-binding protein P (S100P),a member of the S-100 family, is also known as protein S100-P, migration-inducing gene 9 protein (MIG9) and protein S100-E,which contains two EF-hand domains. As for subunit structure,S100P is homodimer and heterodimer with S100A1. S100P may function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, S100P functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. Furthermore,S100P may stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

 

References :

(1) Becker T., et al., 1992, Eur. J. Biochem. 207:541-547.
(2) Koltzscher M., et al., 2003, Mol. Biol. Cell 14:2372-2384.
(3) Arumugam T., et al., 2004, J. Biol. Chem. 279:5059-5065.