Human Reg4 Protein, His Tag

Source : 

Human Reg4, His Tag (RE4-H5221) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Pro 158 (Accession # AAH17089).

 

Molecule : Reg4

 

Synonyms : REG4,GISP,REG-IV,RELP

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : AAH17089

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 16.7 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.7 kDa. The protein migrates as 18 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Regenerating islet-derived protein 4 (REG4) is also known as Gastrointestinal secretory protein (GISP), REG-like protein (RELP). REG4 contains one C-type lectin domain. REG4 has calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. REG4 may be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.

 

References :

(1) Kaemaeraeinen M., et al., 2003, Am. J. Pathol. 163:11-20.
(2) Ho M.R., et al., 2010, J. Mol. Biol. 402:682-695.