Human OX40 / TNFRSF4 / CD134 Protein, Mouse IgG2a Fc Tag, low endotoxin

Source : 

Human OX40, Mouse IgG2a Fc Tag, low endotoxin (OX0-H5252) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Ala 216 (Accession # P43489-1).

 

Molecule : OX40

 

Synonyms : TNFRSF4,OX40,CD134,OX40L receptor,ACT35,TXGP1L

 

Format : Powder

 

Category : Immune Checkpoint Proteins

 

Accession : NP 003318.1

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 47.1 kDa

 

Characteristics :

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 47.1 kDa. The protein migrates as 58-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 0.1 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5

 

Description :

Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) is also known as ACT35 antigen, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, OX40. OX40 / TNFRSF4 contains four TNFR-Cys repeats. TNFRSF4 is receptor for TNFSF4 / OX40L / GP34 and can interacts with TRAF2, TRAF3 and TRAF5.

 

References :

(1) Arch R.H., et al., 1998, Mol. Cell. Biol. 18:558-565.
(2) Kawamata S., et al., 1998, J. Biol. Chem. 273:5808-5814.