Human NTB-A / SLAMF6 Protein, His Tag

Source : 

Human NTB-A, His Tag (NTA-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Met 226 (Accession # Q96DU3-1).

 

Molecule : NTB-A

 

Synonyms : NTB-A,SLAMF6,Ly108,NK-T-B-antigen,CD352,KALI

 

Format : Powder

 

Category : Immune Checkpoint Proteins

 

Accession : NP_001171643.1

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 25.0 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.0 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

The SLAM family of receptors is composed of six members named SLAM (CD150); 2B4 (CD244); Ly-9 (CD229); CD84; natural killer, T and B cell antigen (NTB-A; Ly108 in the mouse. Most, if not all,immune cell types express more than one SLAM family receptor. All six SLAM-related genes are located within a 400–500 kilobase (kb) genomic segment on chromosome 1 in humans and mice. This feature implies that the genes that encode the SLAM family were created by serial gene duplication.

 

References :

(1) Veillette A., et al. 2007, Immunity., 27(5), 698-710.
(2) Detre C., et al. 2010, Semin Immunopathol., 32(2), 157-71.
(3) Nakajima H., et al. 2010, Semin Immunopathol., 32(2), 157-71.