Human IL6R / CD126 Protein (His Tag)

Species : Human

Synonyms : CD126,gp80,IL-6R,IL-6R-1,IL-6RA,IL6Q,IL6RA,IL6RQ

Host : HEK293 Cells

Purity :> 90 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL-6 at 8 £gg/mL (100£gl/well) can bind recombinant human IL6R with a linear range of 1.25-20.0 ng/ml.
2. Measured by its ability to enhance the IL6 activity on M1 mouse myeloid leukemia cells. The ED50 for this effect is typically 10-60 ng/mL.
3. Using the Octet RED System, the affinity constant (Kd) of IL-6R Protein, Human, Recombinant (His Tag) (Cat. 10398-H08H) bound Anti-IL6R Antibody (Cat. 10398-MM08) was 0.1 nM.