Human IL4R / CD124 Protein (His Tag)

Species : Human

Synonyms : CD124,IL-4RA,IL4R,IL4RA

Host : HEK293 Cells

Purity :> 98 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized human IL4R-His (Cat:10402-H08H) at 10 £gg/mL (100 £gl/well) can bind biotinylated human IL4 (Cat:11846-HNAE). The EC50 of biotinylated human IL4 is 20.8-48.5 ng/mL.
2. Measured by its ability to inhibit IL-4 dependent proliferation of TF-1 human erthroleukemic cells. The ED50 for this effect is 2-10 ng/mL in the presence of 2 ng/ml IL-4.