Human IL-20 R beta Protein, Fc Tag

Source : 

Human IL-20 R beta, Fc Tag (ILB-H5258) is expressed from human 293 cells (HEK293). It contains AA Asp 30 - Ala 230 (Accession # AAH63696).

 

Molecule : IL-20 R beta

 

Synonyms : IL20RB,IL-20R2,IL-20R-beta,DIRS1,FNDC6

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : AAH63696

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 49.1 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.1 kDa. As a result of glycosylation, the protein migrates as 50 kDa under reducing (R) condition, and 100 kDa under non-reducing (NR) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 100 mM Glycine, pH7.5

 

Description :

Interleukin-20 receptor subunit beta (IL20RB) is also known as IL-20R2, DIRS1, which belongs to the type II cytokine receptor family. IL20RB / IL-20R2 contains two fibronectin type-III domains. IL20RB / IL-20R2 is widely expressed with highest levels in skin and testis. IL20RB can be fused with IL20RA or IL22RA1 forming heterodimer. The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.

 

References :

(1) Blumberg H., et al., 2001, Cell 104:9-19.
(2) Dumoutier L., et al., 2001, J. Immunol. 167:3545-3549.
(3) Parrish-Novak J., et al., 2002, J. Biol. Chem. 277:47517-47523.