Human IL-1RA / IL1RN Protein

Species : Human

Synonyms : DIRA,ICIL-1RA,IL-1ra,IL-1ra3,IL-1RN,IL1F3,IL1RA,IRAP,MVCD4

Host : E. coli

Purity :> 97 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized human IL1RA at 10 £gg/ml (100 £gl/well) can bind human IL1R2-Fc (Cat:10111-H02H), The EC50 of human IL1R2-Fc (Cat:10111-H02H) is 0.04-0.1 £gg/mL.
2. Measured by its binding ability in a functional ELISA. Immobilized human IL1RA at 10 £gg/ml (100 £gl/well) can bind human IL1R1-Fc (Cat:10126-H02H), The EC50 of human IL1R1-Fc (Cat:10126-H02H) is 0.08-0.2 £gg/mL.
3. Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 250pg/mL IL1a. The EC50 for this effect is typically 3-12 ng/mL.