Human IGFBP6 / IBP-6 Protein (His Tag)

Species : Human

Synonyms : IBP6

Host : HEK293 Cells

Purity :> 96 % as determined by SDS-PAGE

Activity : 1. Measured by its ability to bind human IGF1 (Cat:10598-H24E) in functional ELISA.
2. Measured by its ability to bind human IGF2 (Cat:13032-H24E) in functional ELISA.
3. Measured by its ability to inhibit the biological activity of IGFII on MCF7 human breast adenocarcinoma cells (Karey, K.P. et al. (1988) Cancer Research 48:4083.). The ED50 for this effect is typically 1-5 £gg/mL in the presence of 14 ng/mL human IGFII.