Human IFN-gamma R1 / IFNGR1 Protein, Fc Tag

Source : 

Human IFN-gamma R1, Fc Tag (IF1-H5254) is expressed from human 293 cells (HEK293). It contains AA Glu 18 - Gly 245 (Accession # AAH05333).

 

Molecule : IFN-gamma R1

 

Synonyms : IFNGR1,CD119,CDw119,IFNGR,IFN-gamma-R1

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : AAH05333

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 52.4 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 52.4 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Interferon gamma receptor 1 (IFNGR1) is also known as CD antigen CD119, which belongs to the type II cytokine receptor family. IFNGR1 contains two fibronectin type-III domains and two Ig-like C2-type (immunoglobulin-like) domains. IFNGR1 / CD119 is receptor for interferon gamma. Two receptors bind one interferon gamma (IFNG) dimer.

 

References :

(1) Aguet M., et al., 1988, Cell 55:273-280.
(2) Walter M.R., et al., 1995, Nature 376:230-235.
(3) Jouanguy E., et al., 2000, J. Clin. Invest. 105:1429-1436.