Human HMGB1 / HMG1 Protein (His Tag)

Species : Human

Synonyms : HMG-1,HMG1,HMG3,SBP-1

Host : HEK293 Cells

Purity :> 93 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized human HMGB at 2 £gg/ml (100 £gl/well) can bind human AGER.
The EC50 of human AGER is 0.27 £gg/ml.
2. Measured by its ability to induce TNF-alpha secretion by RAW 264.7 mouse monocyte/macrophage cells.
The ED50 for this effect is typically 20-100£gg/ml.