Human HER2 / ErbB2 Protein

Species : Human

Synonyms : CD340,ENV,ENVW,ERVWE1,HER-2,HER-2/neu,HER2,HERV-7q,HERV-W-ENV,HERV7Q,HERVW,HERVWENV,MLN 19,MLN19,NEU,NGL,TKR1

Host : HEK293 Cells

Purity :> 95 % as determined by SDS-PAGE.

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized Human Her2/ERBB2 (Cat:10004-HCCH) at 2 £gg/ml (100 £gl/well) can bind Herceptin, the EC50?of Herceptin is 7.0-30.0 ng/mL.
2. Measured by its ability to block anti-ErbB2 mediated inhibition of BT474 human breast ductal carcinoma cell proliferation. The ED50 for this effect is 0.3-1.5 £gg/mL in the presence of 0.6 ?g/mL Anti-ErbB2/Her2 Monoclonal Antibody.