Human Glutaredoxin 1 / GLRX1 Protein, His Tag

Source : 

Human Glutaredoxin 1, His Tag (GLX-H5149) is expressed from E.coli cells. It contains AA Met 1 - Gln 106 (Accession # NP_001112362).

 

Molecule : Glutaredoxin 1

 

Synonyms : GLRX,GRX,TTase-1,GLRX1,GRX1

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : NP_001112362

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 12.7 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 12.7 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 150 mM NaCl, pH7.5 with 1 mM DTT

 

Description :

Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.

 

References :

(1) Papov V.V., et al., 1994, Protein Sci. 3:428-434.
(2) Yang Y., et al., 1998, Biochemistry 37:17145-17156.