Human GDF-9

SOURCE: E. coli

PURITY: >98% by SDS-PAGE and HPLC analysis Endotoxin level is <0.1 ng per ug of GDF-9.

MOL. WEIGHT: 31.2 kDa

FORMULATION: Sterile filtered and lyophilized with no additives

RECONSTITUTION: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use.

STORAGE CONDITIONS: The lyophilized GDF-9 is best-stored desiccated below 0oC. Reconstituted GDF-9 should be stored at working aliquots at -20oC.

GDF-9 is a member of the TGF-? superfamily of growth and differentiation factors, and is highly homologous to GDF-3. Unlike most TGF-family members, GDF-9 and GDF-3 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. GDF-9 is expressed in oocytes and is required for normal ovarian folliculogenesis. Recombinant human GDF-9 is a 31.0 kDa non-disulfide-linked homodimer containing two 135 amino acid polypeptide chains.

DESCRIPTION:

USAGE: For Research Use Only! Not to be used in human subjects.