Human Factor XI (Plasma Thromboplastin Antecedent)

Prepared from fresh frozen human plasma. Human Factor XI is a two-chain glycoprotein with molecular weight of 160,000 daltons.  The two chains are identical disulfide bonded polypeptides with molecular weights of 80,000 daltons.  Factor XI is activated to Factor XIa by Factor Xlla. Purity of Factor XI is assessed by SDS-PAGE.  Activity is determined by clotting assay.

Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCI/pH 5.3

*Extinction Coefficient (1%) = 13.1

Molecular Weight = 160,000 daltons