Human FABP3 / H-FABP Protein, His Tag

Source : 

Human FABP3, His Tag (FA3-H5128) is expressed from E.coli cells. It contains AA Met 1 - Ala 133 (Accession # NP_004093).

 

Molecule : FABP3

 

Synonyms : FABP3,H-FABP,FABP11,MDGI,M-FABP,hFABP,O-FABP

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_004093

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 15.7 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.7 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 150 mM NaCl, pH7.5

 

Description :

Fatty acid-binding protein 3 (FABP3) is also known as Heart-type fatty acid binding protein (H-FABP), Mammary-derived growth inhibitor (MDGI), Muscle fatty acid-binding protein (M-FABP), FABP11, which belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. H-FABP / FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABP3 may also contribute to AS160 phosphorylation by maintaining insulin-dependent Akt activation in the cells under a lipotoxic condition.

 

References :

(1) Offner G.D., et al., 1988, Biochem. J. 252:191-198.
(2) Boerchers T., et al., 1990, Mol. Cell. Biochem. 98:127-133.
(3) Kleine AH., et al., 1992, Mol. Cell. Biochem. 116 (1–2): 155–62.