Human FABP2 / I-FABP Protein, His Tag

Source : 

Human FABP2, His Tag (FA2-H5149) is expressed from E.coli cells. It contains AA Ala 2 - Asp 132 (Accession # P12104-1).

 

Molecule : FABP2

 

Synonyms : FABP2,FABPI,I-FABP

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_000125.2

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 16.1 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 16.1 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Fatty acid-binding protein 2 (FABP2), is also known as Fatty acid-binding protein, intestinal (FABPI), Intestinal-type fatty acid-binding protein (I-FABP). FABP2 belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. FABP2 / FABPI is expressed in the small intestine and at much lower levels in the large intestine and is highest expressed in the jejunum. FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

 

References :

(1) Pelsers M.M.A.L., et al., 2003, Clin. Biochem. 36:529-535.
(2) Darimont C., et al., 1999, Am. J. Physiol. 276:G606-G612.