Human Ephrin-B1 / EFNB1 Protein, His Tag

Source : 

Human Ephrin-B1, His Tag (EF1-H5223) is expressed from human 293 cells (HEK293). It contains AA Leu 28 - Gly 232 (Accession # NP_004420).

 

Molecule : Ephrin-B1

 

Synonyms : EFNB1,EFL-3,ELK ligand,ELK-L,EPLG2,LERK2,CFND,CFNS

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_004420

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 23.6 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.6 kDa. The protein migrates as 32-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Ephrin-B1 (EFNB1) is also known as EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2 (LERK-2), which belongs to the ephrin family. EFNB1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNB1 binds to the receptor tyrosine kinases EPHB1 and EPHA1. EFNB1 binds to, and induce the collapse of, commissural axons/growth cones in vitro. EFNB1 may play a role in constraining the orientation of longitudinally projecting axons. EFNB1 interacts with GRIP1 and GRIP2.

 

References :

(1) Zhang Z., et al., 2004, Protein Sci. 13:2819-2824.
(2) Brueckner K., et al., 1999, Neuron 22:511-524.