Human DLL4 Protein (Fc Tag)

Species : Human

Synonyms : Delta-like 4,hdelta2

Host : HEK293 Cells

Purity :> 95 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized Mouse NOTCH1-His (Cat: 50654-M08B) at 2 £gg/ml (100 £gl/well) can bind human DLL4-hFc (Cat: 10171-H02H), the EC50?of human DLL4-hFc is 15-90 ng/mL.
2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 1-8 ?g/mL in the presence of 500 ng/mL recombinant human BMP2.