Human Cystatin SA / CST2 Protein, His Tag

Source : 

Human Cystatin SA, His Tag (CS2-H5224) is expressed from human 293 cells (HEK293). It contains AA Trp 21 - Ala 141 (Accession # AAH62679).

 

Molecule : Cystatin SA

 

Synonyms : CST2,Cystatin-2,Cystatin-SA,Cystatin-S5

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : AAH62679

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 15.2 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.2 kDa. The protein migrates as 15-16 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 150 mM NaCl, pH8.0

 

Description :

Cystatin-2 (CST2) is also known as Cystatin-SA, Cystatin-S5, is a secreted thiol protease inhibitor, which belongs to the cystatin family. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The CST1, CST2, CST4, and CST5 are expressed in differential, tissue-specific patterns. CST2 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level) and is also expressed in submandibular gland and parotid gland.

 

References :

(1) Dickinson D.P., et al., 2002, DNA Cell Biol. 21:47-65.
(2) Ryan C.M., et al., 2010, J. Am. Soc. Mass Spectrom. 21:908-917.