Human Cystatin D / CST5 Protein, His Tag

Source : 

Human Cystatin D, His Tag (CS5-H5220) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Val 142 (Accession # AAH69514).

 

Molecule : Cystatin D

 

Synonyms : CST5,Cystatin-5,Cystatin-D

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : AAH69514

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 14.8 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.8 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Cystatin-5 (CST5) is also known as Cystatin-D, is a secreted thermostable protein, which belongs to the cystatin family. CST5 is a cysteine proteinase inhibitor that possibly plays a protective role against proteinases present in the oral cavity. The order of preference for inhibition is cathepsin S > cathepsin H > cathepsin L > cathepsin B. CST5 / cystatin-D may play a protective role against proteinases present in the oral cavity.

 

References :

(1) Balbin M., et al., 1994, J. Biol. Chem. 269:23156-23162.
(2) Ryan C.M., et al., 2010, J. Am. Soc. Mass Spectrom. 21:908-917.