Human CTLA4 / CD152 Protein (His Tag)

Species : Human

Synonyms : ALPS5,CD,CD152,CELIAC3,CTLA-4,GRD4,GSE,IDDM12

Host : HEK293 Cells

Purity :> 90 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA.
2. Immobilized human CTLA4 (cat: 11159-H08H) at 10 £gg/mL (100 £gl/well) can bind human B7-1/Fc (cat: 10698-H03H), The EC50 of human B7-1/Fc (cat: 10698-H03H is 14 ng/mL.
3. Immobilized human CTLA4 (cat: 11159-H08H) at 10 £gg/mL (100 £gl/well) can bind human B7-2/Fch (cat: 10699-H03H), The EC50 of human B7-2/Fch (cat: 10699-H03H) is 53 ng/mL.
4. Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.05-0.3£gg/mL when stimulated with 1 £gg/mL Recombinant Human B7?1/CD80.