Human CLEC3B / Tetranectin Protein, His Tag, low endotoxin

Source : 

Human CLEC3B, His Tag, low endotoxin (CLB-H5226) is expressed from human 293 cells (HEK293). It contains AA Glu 22 - Val 202 (Accession # AAH11024).

 

Molecule : CLEC3B

 

Synonyms : CLEC3B,Tetranectin,TN,TNA

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : AAH11024

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 21.1 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 21.1 kDa. The protein migrates as 22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 0.1 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

C-type lectin domain family 3 member B (CLEC3B) is also known as Tetranectin, Plasminogen kringle 4-binding protein, is a secreted homotrimer. CLEC3B contains 1 C-type lectin domain and mainly found in plasma. Tetranectin / CLEC3B binds to plasminogen and to isolated kringle 4. CLEC3B may be involved in the packaging of molecules destined for exocytosis. Decreased plasma Tetranectin or increased Tetranectin in stroma of cancers correlates with cancer progression and adverse prognosis.

 

References :

(1) Fuhlendorff J., et al., 1987, Biochemistry 26:6757-6764.
(2) Jaquinod M., et al., 1999, Biol. Chem. 380:1307-1314.