Human Chitinase 3-like 1 / CHI3L1 Protein, His Tag

Source : 

Human CHI3L1, His Tag (CH1-H5228) is expressed from human 293 cells (HEK293). It contains AA Tyr 22 - Thr 383 (Accession # AAH38354).

 

Molecule : Chitinase 3-like 1

 

Synonyms : CHI3L1,YKL-40,CGP-39,GP-39,ASRT7

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : AAH38354

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 41.2 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.2 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Chitinase-3-like protein 1 (CHI3L1) is also known as Cartilage glycoprotein 39 (CGP-39), YKL-40, which belongs to the glycosyl hydrolase 18 family. CHI3L1 is present in activated macrophages, articular chondrocytes, synovial cells as well as in liver. CHI3L1 may play a role in defense against pathogens, or in tissue remodeling and also may play an important role in the capacity of cells to respond to and cope with changes in their environment.

 

References :

(1) Renkema G.H., et al., 1998, Eur. J. Biochem. 251:504-509.
(2) Houston D.R., et al., 2003, J. Biol. Chem. 278:30206-30212.