Human CEACAM-5 / CD66e Protein, His Tag

Source : 

Human CEACAM-5, His Tag (CE5-H5226) is expressed from human 293 cells (HEK293). It contains AA Lys 35 - Ala 685 (Accession # P06731).

 

Molecule : CEACAM-5

 

Synonyms : CEACAM-5,CD66e,CEA,Meconium antigen 100

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_004354

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 72.2 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 72.2 kDa. The protein migrates as 100-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.

 

References :

(1) Taheri M., et al., 2000, J. Biol. Chem. 275:26935-26943.
(2) Korotkova N., et al., 2008, Mol. Microbiol. 67:420-434.