Human CD9 Protein, His Tag

Source : 

Human CD9, His Tag (CD9-H5220) is expressed from human 293 cells (HEK293). It contains AA Ser 112 - Ile 195 (Accession # P21926-1).

 

Molecule : CD9

 

Synonyms : CD9,MIC3,TSPAN29,GIG2,MRP1,BTCC1,DRAP27,5H9

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : NP_001760.1

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 11.6 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.6 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

CD9 antigen is also known as tetraspanin-29 (TSPAN29), 5H9 antigen, Leukocyte antigen MIC3 (MIC3), Motility-related protein, is a multi-pass membrane protein which belongs to the tetraspanin (TM4SF) family or the transmembrane 4 superfamily. CD9 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. TSPAN29 is found on the surface of exosomes. MIC3 Involved in platelet activation and aggregation, regulates paranodal junction formation and also Involved in cell adhesion, cell motility and tumor metastasis. CD9 antigen also seems to be a key part in the egg-sperm fusion during mammalian fertilization.

 

References :

(1) Katz F., et al., 1984, Eur J Immunol 13 (12): 1008–1013.
(2) François Le Naour, 2000, Science 287 (5451): 319–321.
(3) Ikeyama S., et al., 1993, J. Exp. Med. 177:1231-1237.
(4) Masellis-Smith A., et al., 1994, J. Immunol. 152:2768-2777.
(5) Higginbottom A., et al., 2003, Biochem. Biophys. Res. Commun. 311:208-214.