Human CD72 Protein, Fc Tag

Source : 

Human CD72, Fc Tag (CD2-H5251) is expressed from human 293 cells (HEK293). It contains AA Arg 117 - Asp 359 (Accession # AAH30227).

 

Molecule : CD72

 

Synonyms : CD72,Lyb-2,Lyb2

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : AAH30227

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 54.2 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 54.2 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 100 mM Glycine, pH7.5

 

Description :

B-cell differentiation antigen CD72 is also known as Lyb-2. CD72 contains one C-type lectin domain. CD72 is a protein active in the immune system of animals. CD72 consists of two identical halves, each of about 39-43 kD, and is a C-type lectin. Its primarily locus of expression is B-cells, where it appears to mediate aspects of B-cell - T-cell interaction. CD72 plays a role in B-cell proliferation and differentiation. CD72 is a ligand for CD5.

 

References :

(1) von Hoegen I., et al., 1990, J. Immunol. 144:4870-4877.