Human CD52 Protein, Fc Tag

Source : 

Human CD52, Fc Tag (CD2-H525a) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ser 36 (Accession # P31358-1).

 

Molecule : CD52

 

Synonyms : CDW52,HE5,CD52,CAMPATH-1 antigen

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : NP_001794.2

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 27.9 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 38-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : Tris with Glycine, Arginine and NaCl, pH7.5

 

Description :

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs).ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.

 

References :

(1) Zhao Y., et al., 2017 ,Immunogenetics.
(2) Hersh C., et al., 2014, Immunotherapy. 6(3):249-59.
(3) Zinzani PL., et al., 2012, Leuk Lymphoma. 53(5):789-9