Human CD37 Protein, Fc Tag

Source : 

Human CD37, Fc Tag (CD7-H526x) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Asn 240 (Accession # AAI06753).

 

Molecule : CD37

 

Synonyms : CD37,Tspan-26,TSPAN26

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : AAI06753

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 41.6 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 41.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : Tris with Glycine, Arginine and NaCl, pH7.5

 

Description :

Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.

 

References :

(1) Virtaneva KI., et al., 1993, Immunogenetics 37 (6): 461–465.
(2) Puls KL., et al., 2004, J. Immunol. 172 (5): 2953–61.
(3) Angelisová P., et al., 1994, Immunogenetics 39 (4): 249–56.