Human CD229 / SLAMF3 Protein, His Tag

Source : 

Human CD229, His Tag (CD9-H52H6) is expressed from human 293 cells (HEK293). It contains AA Lys 48 - Lys 454 (Accession # Q9HBG7-1).

 

Molecule : CD229

 

Synonyms : SLAMF3,LY9,Ly-9,hly9,Ly9

 

Format : Powder

 

Category : Immune Checkpoint Proteins

 

Accession : NP_002339.2

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 46.7 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.7 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

CD229, also known as Ly9 and SLAMF3, is a 120 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Signaling lymphocyte activation molecule (SLAM) family receptors are critically involved in modulating innate and adaptive immune responses. CD229 is expressed on T and B cells, thymocytes, and more weakly on NK cells. Homophilic binding between CD229 molecules is mediated by the N-terminal Ig-like domain.

 

References :

(1) Bhat R., et al. 2006, J Leukoc Biol., 79(3), 417-24.
(2) de la Fuente MA., et al. 2001, Blood., 97(11), 3513-20.
(3) Graham DB., et al. 2006, J Immunol., 176(1), 291-300.