Human Arginase 1 / ARG1 Protein, His Tag

Source : 

Human Arginase 1, His Tag (AR1-H5228) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Lys 322 (Accession # NP_000036).

 

Molecule : Arginase 1

 

Synonyms : ARG1,Arginase-1

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : NP_000036

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 35.8 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.8 kDa. The protein migrates as 35-38 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : 50 mM Tris, 150 mM NaCl, pH7.5

 

Description :

Arginase-1 (ARG1) is also known as Liver-type arginase, Type I arginase, which belongs to the arginase family. Arginase-1 / ARG1 is a manganese-containing enzyme. The reaction catalyzed by this enzyme is: arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle. Defects in Arginase-1 / ARG1 are the cause of argininemia (ARGIN).

 

References :

(1) Ikemoto M., et al., 1990, Biochem. J. 270:697-703.
(2) Di Costanzo L., et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102:13058-13063.
(3) Di Costanzo L., et al., 2007, J. Am. Chem. Soc. 129:6388-6389.